DourineClinical signs, differential diagnosis, treatment and prevention in horses.
Overview
A chronic venereal disease of horses, transmitted during mating. Trypanosoma equiperdum, transmitted directly during coitus (not by an insect vector, unlike most trypanosomes).
Clinical signs
- The severity of the clinical syndrome varies depending on the strain of the trypanosome and the general health of the horse population.
Predisposing factors
- Occurrence Dourine is endemic in Asia, Africa, southeastern Europe, and Central America.
Look-alikes to rule out
Equine Infectious Anemia (EIA) Equine Infectious Anemia (EIA / Swamp Fever) Equine coital exanthema
Treatment
TREATMENT AND CONTROL None is recommended. Many trypanocidal drugs have been used in the treatment of dourine, but results are variable, chronic cases in particular are unresponsive to treatment.
Drugs mentioned: Quinapyramine Diminazene
Prevention
Stamping out / elimination (complete elimination of dourine from India is a good example of this control concept) Image: Page.
Source
A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goat by ELSEVIER — Dourine (Maladie Du Coit)
A Textbook of Preventive Veterinary Medicine by Amalendu Chakrabarti (Page 26)
MSD Veterinary Manual — Trypanosomiasis in Animals (accessed 2026-08-11)
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