FieldDxAtipamezoleDose, contraindications and adverse effects for Cats, Cattle, Dogs, Goats, Horses, Poultry and Sheep.
What it is used for
Alpha-2 adrenergic receptor antagonist. Reversal of sedative and analgesic effects of alpha-2 agonists (medetomidine, dexmedetomidine).
Dose by species
Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.
How it works
Competitively blocks central and peripheral alpha-2 adrenergic receptors.
Do not use in
Hypersensitivity.
Main adverse effects
Potential adverse effects include occasional vomiting, diarrhea, hypersalivation, tremors, and brief excitation or apprehensiveness. Transient fluctuations in blood pressure (ie, hypotension followed by hypertension) and increased respiratory rate may occur. Severe arterial hypotension has been noted in cats. In reptiles, IV administration reportedly can cause profound hypotension.
Monitoring
■ Level of sedation and analgesia ■ Heart rate and blood pressure ■ Body temperature
Source
Plumb (p. 106)
Plumb's Veterinary Drug Handbook, 10th Edition
Papich Handbook of Veterinary Drugs, 5th Edition
Condensed and attributed, never reproduced whole. Open the full entry in the app.