FieldDxAtropineDose, contraindications and adverse effects for Cats, Cattle, Dogs, Goats, Horses, Pigs, Poultry and Sheep.
What it is used for
Anticholinergic / parasympatholytic agent. Preanesthetic to control secretions; treatment of bradycardia or organophosphate poisoning.
Dose by species
Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.
How it works
Competitive antagonist of acetylcholine at muscarinic cholinergic receptors.
Do not use in
Severe tachycardia, mechanical GI or urinary obstruction, or glaucoma.
Main adverse effects
Adverse effects are exacerbations of the drug’s pharmacologic effects and are generally dose related. At standard doses, effects tend to be mild in relatively healthy animals. The more severe effects typically occur with high or toxic doses. GI effects can include dry mouth (ie, xerostomia), increased viscosity of secretions, dysphagia, constipation, and vomiting. Respiratory secretions may become viscous and more difficult to clear from the airway.
Monitoring
Dependent on dose and indication: ■ Heart rate and rhythm ■ Blood pressure ■ GI motility (via auscultation) in horses and potentially in ruminants ■ Urination, defecation capability ■ Hydration; dry mouth and secretions (eg, respiratory)
Conditions it is used for
Mare reproductive loss syndrome Contagious conjunctivokeratitis Blight Pathologic Second-Degree Atrioventricular Block Pathologic Second-Degree AV Block
Source
Plumb (p. 112); Papich (pp. x, 21)
Plumb's Veterinary Drug Handbook, 10th Edition
Papich Handbook of Veterinary Drugs, 5th Edition (p. 71)
Condensed and attributed, never reproduced whole. Open the full entry in the app.