Chorionic GonadotropinDose, contraindications and adverse effects for Cats, Cattle, Dogs, Goats, Horses, Pigs, Poultry and Sheep.
What it is used for
Human chorionic gonadotropin (hCG); mimics LH to induce ovulation or stimulate gonadal hormone production in reproductive protocols. The veterinary FDA-approved human chorionic gonadotropin (hCG) product is used parenterally in cows for the treatment of nymphomania (frequent or constant heat) caused by cystic ovaries and as an aid to improve spawning function in male and female brood finfish. It has been used for other purposes in several species; refer to the Dosages section for more information.
Dose by species
Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.
How it works
Chorionic gonadotropin (CG) mimics the effects of luteinizing hormone (LH). In males, CG stimulates the differentiation of testicular interstitial (Leydig) cells and produces androgens. Hormonal treatment of cryptorchidism with human chorionic gonadotropin (hCG) is controversial in humans and domestic animals.
Do not use in
In humans, chorionic gonadotropin (hCG) is contraindicated in patients with prostatic carcinoma or other androgen-dependent neoplasias, precocious puberty, or those with a previous hypersensitivity reaction to hCG. No labeled contraindications for veterinary patients were noted, but these human contraindications should be used as guidelines. Antibody production to hCG has been reported after repetitive use
Main adverse effects
Repeated doses of chorionic gonadotropin (hCG) may cause abortion in mares prior to the 35th day of pregnancy, possibly because of 260 Chorionic Gonadotropin increased estrogen levels. Potentially, hypersensitivity reactions are possible with this agent. Anaphylactic reactions are rare, and several practitioners have anecdotally reported mares showing transient hives and respiratory distress immediately following hCG administration.
Source
Plumb's Veterinary Drug Handbook, 10th Edition
MSD Veterinary Manual โ Control of Reproduction in Small Animals (accessed 2026-08-12)
Condensed and attributed, never reproduced whole. Open the full entry in the app.