FieldDxDiltiazemDose, contraindications and adverse effects for Cats, Dogs and Horses.
What it is used for
Benzothiazepine calcium-channel blocker. Controlling heart rhythm.
Dose by species
Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.
How it works
Calcium channel blockade.
Do not use in
Diltiazem is contraindicated in patients hypersensitive to it or those with severe hypotension (less than 90 mm Hg systolic), sinus node dysfunction (eg, sick sinus syndrome), high-grade atrioventricular (AV) block (unless a functioning artificial pacemaker is in place), or radiographically documented pulmonary congestion.
Main adverse effects
Diltiazem appears to be well tolerated at recommended doses. One feline study found that the 60 mg sustained-release pellet (9.3 to 14.8 mg/kg) was associated with lethargy, GI disturbances, and weight loss in 36% of treated cats. GI disturbances were recognized within one week, and weight loss was detected after 2 to 6 months of treatment.
Monitoring
■ Baseline and periodic heart rate, ECG, and blood pressure ■ Adverse effects
Source
Plumb (p. 377); Papich (p. 153).
Plumb's Veterinary Drug Handbook, 10th Edition
Papich Handbook of Veterinary Drugs, 5th Edition (p. 277)
Condensed and attributed, never reproduced whole. Open the full entry in the app.