EthanolDose, contraindications and adverse effects for Cats, Dogs and Horses.

What it is used for

Alcohol. Instructions for making dilutions from stock solutions (vodka) provided. Ethylene glycol (antifreeze) toxicosis.

Dose by species

Dose5.5 mL/kg IV every 4 hoursDogs

Dose8.6 mL/kg IVDogs

Dose1–1.4 mL/kg PODogs

Dose5 mL/kg IV every 6 hoursCats

Dose8.6 mL/kg IVCats

Dose1–1.4 mL/kg POCats

Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.

How it works

Inhibits alcohol dehydrogenase (competitively).

Do not use in

Cats must be treated within 3 hours of ethylene glycol ingestion.

Main adverse effects

General adverse effects associated with ethanol are CNS depression and respiratory depression. A high risk for hypothermia and respiratory arrest is associated with high blood levels. Ethanol’s effects on antidiuretic hormone (ADH; vasopressin) may enhance diuresis. As ethylene glycol may also cause diuresis, fluid and electrolyte therapy requirements need to be monitored and managed. Hypoglycemia, hypocalcemia, and metabolic acidosis may be seen

Monitoring

■ Alcohol blood levels (and ethylene glycol or methanol levels). NOTE: In humans, blood ethanol levels should be maintained at 100 – 130 (some say up to 200) mg/dL (21.7 – 28.2 milliMoles/L).

Conditions it is used for

Ethylene Glycol Toxicosis

Source

Plumb (p. 487).

Plumb's Veterinary Drug Handbook, 10th Edition

Condensed and attributed, never reproduced whole. Open the full entry in the app.