Hydroxyethyl Starch ColloidsDose, contraindications and adverse effects for Cats, Dogs, Horses and Poultry.

Synthetic starch-based colloid; a plasma volume expander used in circulatory shock. Hydroxyethyl starch (HES) colloids are used in the adjunctive treatment of hypovolemia and states of low oncotic pressure (ie, hypoalbuminemia) in small and large animal species. They can be used to increase and support colloid osmotic pressure (COP). HES therapy can be considered when crystalloid therapy is not sufficiently improving or maintaining blood volume, when there is a need to pro

Hydroxyethyl starch (HES) colloid acts as a plasma volume expander by increasing the oncotic pressure within the intravascular space similarly to either dextran or albumin. Maximum volume expansion occurs within a few minutes of the completion of infusion.

The veterinary-labeled product (6% hydroxyethyl starch [HES] colloid 130/0.4) lists the following contraindications: known hypersensitivity to hydroxyethyl starch, fluid overload (eg, pulmonary edema, congestive heart failure), renal failure with oliguria or anuria not related to hypovolemia, patients receiving dialysis treatment, severe hypernatremia or hyperchloremia, or intracranial bleeding.

Hydroxyethyl starch (HES) colloids can affect platelet function and coagulation times and alter factor VIII and von Willebrand factor. At recommended dosages, HES may cause changes in clotting times and platelet counts due to direct (precipitation of factor VIII) and dilutional causes. A retrospective study in dogs showed that he- 626 Hydroxyethyl Starch (HES) Colloids tastarch can significantly increase PTT, but did not affect patient survival rates.

■ Hydration status and signs of fluid overload (eg, increased respiratory rate and effort, pulmonary edema)1 ■ Clinical signs of anaphylactic-like reactions, including worsening signs of shock and pruritus ■ Renal chemistry panel and urine output ■ Serum electrolytes, acid-base balance ■ Colloid…