Polyethylene Glycol 3350Dose, contraindications and adverse effects for Cats and Dogs.

Osmotic laxative powder (Miralax). Reconstituted solutions must be refrigerated and used within 24 hours. Constipation, bowel evacuation.

Osmotic agent; draws and retains water in the intestinal lumen to soften stool and promote peristalsis.

Not specified in source. ARCI designates as class 5 substance.

Vomiting, nausea, and cramping are possible. Vomiting occurring during acute administration of PEG 3350 with electrolytes may be managed with metoclopramide or by reducing the flow rate by 50% for one hour, then resuming the original rate. Long-term use could potentially cause hyponatremia, dehydration, or hyperkalemia. If PEG 3350 is absorbed systemically, oxidative injury to red blood cells could occur in cats, but this has not been documented to date.

■ Fluid and electrolyte status; in particular, if using high doses or with long-term use ■ Clinical efficacy (eg, production of feces) ■ Adverse effects, especially vomiting and aspiration when a large volume is administered