FieldDx

Drug reference · Streptomycin

StreptomycinDose, contraindications and adverse effects for Cattle, Horses, Pigs and Poultry.

What it is used for

An aminoglycoside antibiotic, narrow-spectrum against aerobic gram-negative bacteria. Active against Pasteurella spp, E. coli, Salmonella spp, Campylobacter fetus, Leptospira spp, Brucella spp, and Mycobacterium tuberculosis.

Dose by species

Dose11 mg/kg IM q12hCattle
Dose11 mg/kg IM q12hSwine
Dose11 mg/kg IM q12hHorses
Dose22–33 mg/kg PO q24hPoultry
Dose22–33 mg/kg PO q24hCattle
Dose22–33 mg/kg POSwine

Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.

How it works

An aminoglycoside; inhibits bacterial protein synthesis. Narrow spectrum, mainly aerobic gram-negative organisms.

Do not use in

Aminoglycosides are nephrotoxic and ototoxic. Kidneys need a drug-free period between courses — the drug accumulates in renal tissue and repeated courses raise the risk of toxicity.

Main adverse effects

Nephrotoxicity and ototoxicity, shared across all aminoglycosides. Ototoxic effects (vestibular, cochlear) may be irreversible.

Conditions it is used for

Anthrax Bovine Tuberculosis Tularemia Streptococcal Lymphadenitis of Swine Vibriosis Traumatic Reticuloperitonitis

Similar drugs

Gentamicin, Systemic Paromomycin

Source

MSD Veterinary Manual — Aminoglycosides (accessed 2026-08-10)

Condensed and attributed, never reproduced whole. Open the full entry in the app.