SulfadimethoxineDose, contraindications and adverse effects for Cats, Cattle and Dogs.

Sulfonamide antibiotic and anticoccidial; labeled as Albon or Bactrovet. Susceptible bacterial or protozoal infections.

Sulfonamide antimicrobial action.

Do not administer in animals with sensitivity to sulfonamides. Doberman pinschers may be more sensitive than other canine breeds to reactions from sulfonamides. Use cautiously in this breed.

Adverse effects associated with sulfonamides include allergic reactions, type II and III hypersensitivity, arthropathy, anemia, thrombocytopenia, hepatopathy, hypothyroidism (with prolonged therapy), KCS, and skin reactions. Dogs may be more sensitive to sulfonamides than other animals because dogs lack the ability to acetylate sulfonamides to metabolites. Other more toxic metabolites may persist.

Sulfonamides are known to decrease T4 concentrations in dogs after 6 weeks of treatment. Susceptibility testing: CLSI breakpoint for susceptible organisms is ≤256 mcg/mL, but according to CLSI, susceptibility tests for sulfonamides should only be used to interpret urinary bacteria isolates.

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.