FieldDx

Drug reference · Toltrazuril

ToltrazurilDose, contraindications and adverse effects for Cats, Dogs and Horses.

What it is used for

Triazine antiprotozoal agent. Parent drug of ponazuril (toltrazuril sulfone). Coccidiocidal. Coccidiosis in calves, lambs, piglets, and poultry. Fecal coccidiosis in shelter dogs and cats.

Dose by species

Dose20 mg/kg POAll listed species
Dose5–20 mg/kg PO once dailyCamelids
Dose5–10 mg/kg PO q24hCats
Dose30 mg/kg once dailyCats
Dose10–30 mg/kg PO q24hDogs
Dose5–10 mg/kg PO q24hHorses

Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.

How it works

Coccidiocidal triazine antiprotozoal; targets the plastid body of Apicomplexa.

Do not use in

Not specified in source. Not for use in suckling or barbecue pigs.

Main adverse effects

Administration of 50 mg/kg to horses (5 and 10 times the recommended dose) produced minor adverse effects, according to the manufacturer. There were minimal changes in the serum analysis.

Monitoring

No specific monitoring is necessary. Fecal analysis should be performed to assess the effects for treating intestinal protozoa.

Conditions it is used for

Coccidiosis Coccidiosis (Eimeria and Isospora Infestation)

Source

Papich (p. 128); Plumb (pp. 1041, 1256, 1257).

Papich Handbook of Veterinary Drugs, 5th Edition (p. 919)

Condensed and attributed, never reproduced whole. Open the full entry in the app.