FieldDx

Drug reference · Tylosin

TylosinDose, contraindications and adverse effects for Cats, Cattle, Dogs and Pigs.

What it is used for

Macrolide antibiotic. Labeled as Tylan or Tylocine. Chronic diarrhea in dogs; respiratory and livestock infections.

Dose by species

Dose7–15 mg/kg PO q12–24hDogs
Dose8–11 mg/kg IM q12hDogs
Dose12–20 mg/kg q8hDogs
Dose7–15 mg/kg PO q12–24hCats
Dose8–11 mg/kg IM q12hCats
Dose8.8 mg/kg IM q12hSwine

Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.

How it works

Macrolide class; binds 50S ribosomal subunit.

Do not use in

Do not administer orally to rodents or rabbits. Do not administer to horses. Avoid IV administration. Do not inject more than 10 mL in one IM site to avoid local reactions.

Main adverse effects

Tylosin may cause diarrhea in some animals. However, for oral treatment for colitis in dogs, it has been administered for several months with safety. Skin reactions have been observed in pigs. Oral administration to horses has been fatal.

Monitoring

No specific monitoring is necessary.

Withdrawal

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.

Conditions it is used for

Bovine chronic diarrhea Contagious Agalactia Contagious Caprine Pleuropneumonia

Source

Plumb (pp. 1284, 1286, 1543).

Papich Handbook of Veterinary Drugs, 5th Edition (p. 953)

Condensed and attributed, never reproduced whole. Open the full entry in the app.