AlbendazoleDose, contraindications and adverse effects for Cats, Cattle, Dogs, Goats, Horses, Poultry and Sheep.
What it is used for
Broad-spectrum benzimidazole anthelmintic. Treatment of nematodes, trematodes, cestodes, and protozoa in cattle, sheep, and nonlactating goats.
Dose by species
Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.
How it works
Anthelmintic; disrupts microtubule assembly and inhibits tubulin polymerization.
Do not use in
Hepatic failure, first trimester of pregnancy, lactating does, and female dairy cattle of breeding age. Extra-label use in dogs, cats, crias, pigeons, or doves is not recommended due to toxicity.
Main adverse effects
Adverse effects include anorexia, lethargy, and bone marrow toxicity. Leukopenia and thrombocytopenia are possible in dogs and cats. Albendazole has an affinity for rapidly dividing cells and may cause toxicity to bone marrow and intestinal epithelium. High doses have been associated with bone marrow toxicity in dogs and cats, and it should be used cautiously in small animals. In other species, at approved doses, there has been a wide margin of safety.
Monitoring
Monitor CBC in animals experiencing signs suspicious of adverse effects. If high doses are accidentally administered to small animals, CBC should be examined for evidence of suppression.
Withdrawal
A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.
Conditions it is used for
Similar drugs
Fenbendazole Ivermectin Levamisole Moxidectin/Moxidectin Praziquantel/Praziquantel
Source
Plumb (pp. 20, 152); Papich (pp. x, 31)
Papich Handbook of Veterinary Drugs, 5th Edition
Condensed and attributed, never reproduced whole. Open the full entry in the app.