CarprofenDose, contraindications and adverse effects for Cats, Cattle, Dogs, Horses, Pigs and Sheep.

Nonsteroidal anti-inflammatory drug (NSAID). Alleviation of pain and inflammation.

Anti-inflammatory and analgesic agent.

Do not use in cats at doses intended for dogs. Do not administer to animals prone to GI ulcers. Do not administer with ulcerogenic drugs such as corticosteroids. If a patient has had previous adverse effects from NSAIDs, carprofen should be used cautiously.

The safety of carprofen in dogs was determined by the sponsor during preclinical studies. The most common adverse effect in dogs has been in the GI tract (vomiting, anorexia, and diarrhea). GI ulcers, perforation, and bleeding are uncommon in dogs but possible. In rare cases, carprofen has caused idiosyncratic acute hepatic toxicity in dogs. Signs of toxicity usually appear 2–3 weeks after exposure.

After administration has begun, one should monitor hepatic enzymes for evidence of drug-induced hepatic toxicity approximately 7–14 days after treatment has started. If liver enzymes are elevated, discontinue the medication and contact the drug manufacturer.

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.