FurosemideDose, contraindications and adverse effects for Cats, Dogs and Horses.

High-ceiling loop diuretic. Congestive heart failure, pulmonary edema, ascites.

Inhibits Na+/K+/2Cl- cotransporter in ascending loop of Henle.

Severe dehydration, anuria, electrolyte depletion.

Adverse effects are primarily related to diuretic effect (loss of fluid and electrolytes). In dogs, hyponatremia is more common than hypokalemia. Tolerance and activation of the renin–angiotensin–aldosterone system (RAAS) occur with repeated administration, in which the diuretic effect is attenuated. When administered to dogs at a dosage of 2 mg/kg q12h, it significantly increased RAAS activity by day 5 of treatment.

Monitor electrolyte concentrations (particularly potassium) and hydration status in patients during treatment.

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.