AmoxicillinDose, contraindications and adverse effects for Cats, Cattle, Dogs and Horses.

What it is used for

Aminopenicillin class beta-lactam antibiotic. Susceptible bacterial infections of skin, soft tissue, and urinary tract.

Dose by species

Dose22 mg/kg PO q12hDogs and Cats

Dose12.5 mg/kg PO q12hCats

Dose10–22 mg/kg PO q8–12hCalves

Dose6.6–22 mg/kg PO q8–12hCattle and horses

Doses are shown as published, not averaged across sources. Enter the animal’s body weight in the interactive drug guide to calculate the amount.

How it works

Time-dependent bactericidal action; inhibits cell wall synthesis.

Do not use in

Hypersensitivity to penicillins or beta-lactams.

Main adverse effects

Amoxicillin is usually well tolerated. Allergic reactions are possible. Diarrhea and vomiting are common with oral doses. Oral administration to horses or cattle can cause diarrhea or enteritis.

Monitoring

Susceptibility testing: For testing for susceptibility, the CLSI recommends using ampicillin to test for amoxicillin susceptibility. The CLSI breakpoint for susceptible organisms is ≤0.25 mcg/mL for staphylococci, streptococci, and gramnegative bacilli.

Withdrawal

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.

Conditions it is used for

Anthrax Melioidosis Streptococcus suis Infection of Young Pigs Cystitis Watery Mouth of Lambs Recurrent Cystitis Prophylaxis

Source

Plumb (p. 67); Papich (pp. x, 16)

Papich Handbook of Veterinary Drugs, 5th Edition (p. 45)

Condensed and attributed, never reproduced whole. Open the full entry in the app.