AmpicillinDose, contraindications and adverse effects for Cats, Cattle, Dogs and Horses.

Aminopenicillin class beta-lactam antibiotic. Susceptible Gram-positive and Gram-negative infections.

Time-dependent bactericidal action; inhibits cell wall mucopeptide synthesis.

Known history of hypersensitivity to penicillins or cephalosporins.

Adverse effects of penicillin drugs are most commonly caused by drug allergy. This can range from acute anaphylaxis when administered IV to other signs of allergic reaction when other routes are used. When used for prophylaxis during surgery, ampicillin can be administered IV to anesthetized patients without affecting cardiovascular parameters. Diarrhea is possible when administered orally, especially with high doses.

Susceptibility testing: For testing for susceptibility, CLSI break point for sensitive organisms is #0.25 mcg/mL for staphylocicci, streptococci, and gram-negative bacilli. For canine urinary tract pathogens, use a break point of #8 mcg/mL. For cattle pathogens, use a break point of #0.25 mcg/mL.

A withdrawal interval is stated for this drug. It depends on the formulation, route and dose, so read the exact wording in the interactive drug guide before treating a food animal.